Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 18 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Iron (elemental) (from 90 mg Ferrous Bisglycinate)(Ferrochelâ„¢)
18 mg
100%
Top Medical Research Studies
8
We explored how iron influences food poisoning, particularly in the context of campylobacteriosis, a common foodborne illness. Our focus was on the effects of deferoxamine (DESF), an iron-chelating compound, when administered orally to mice before they were infected.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
Read More
Most Useful Reviews
9
Increased energy levels
8 people found this helpful
Excellent! I recommend it to active girls! Initially, I took 36 units (NOW Foods Iron Double Strength) as two pieces a day, but here the dosage is 18 units, so I now take four. I can't imagine life without this supplement. My sports and dance routine was exhausting, leaving me depleted. After starting NOW Foods Iron, I felt revitalised and strong again. I truly recommend it!
Read More
9
Iron raised levels
5 people found this helpful
This chelated iron works remarkably well in raising iron levels. I took two capsules daily, and while it may not suffice for a significant deficit, it helped me. I added vitamin C to my diet afterwards, and after 8 weeks, my ferritin levels rose and I felt no constipation, thanks to my high-fiber diet.
Read More
9
Good daily supplement
1 people found this helpful
These are effective daily iron supplements if dietary sources are inadequate. They do not upset my stomach or cause a tummy ache, which is a significant bonus! The only downside is the capsule size, which is relatively large. I wish they were available in gel capsules for easier swallowing.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We explored how iron influences food poisoning, particularly in the context of campylobacteriosis, a common foodborne illness. Our focus was on the effects of deferoxamine (DESF), an iron-chelating compound, when administered orally to mice before they were infected.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
Read More
User Reviews
USERS' SCORE
Good
Based on 18 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Increased energy levels
8 people found this helpful
Excellent! I recommend it to active girls! Initially, I took 36 units (NOW Foods Iron Double Strength) as two pieces a day, but here the dosage is 18 units, so I now take four. I can't imagine life without this supplement. My sports and dance routine was exhausting, leaving me depleted. After starting NOW Foods Iron, I felt revitalised and strong again. I truly recommend it!
Read More
9
Iron raised levels
5 people found this helpful
This chelated iron works remarkably well in raising iron levels. I took two capsules daily, and while it may not suffice for a significant deficit, it helped me. I added vitamin C to my diet afterwards, and after 8 weeks, my ferritin levels rose and I felt no constipation, thanks to my high-fiber diet.
Read More
9
Good daily supplement
1 people found this helpful
These are effective daily iron supplements if dietary sources are inadequate. They do not upset my stomach or cause a tummy ache, which is a significant bonus! The only downside is the capsule size, which is relatively large. I wish they were available in gel capsules for easier swallowing.
Read More
9
Iron supplementation works
6 people found this helpful
My hemoglobin was low, and as someone who doesn't enjoy eating meat, I usually struggle with iron supplements. However, this one caused no discomfort and my blood tests showed normal hemoglobin levels. I also noticed increased energy. Thank you; I'm ready to order again!
Read More
7.5
Iron improves menstruation
6 people found this helpful
After searching for a safe, vegetarian iron supplement, I found this one, which doesn't cause any stomach discomfort or constipation. I appreciate that I don't have to wait an hour before eating or avoid dairy or coffee. Following the recommended dosage, I feel reassured about potential poisoning. Within two weeks of starting it, my menstruation returned to normal. Knowing that Now Foods is a family-run company gives me more confidence in their products. Supplements can be beneficial or harmful, so one must choose wisely.
Read More
Frequently Asked Questions
7.5
Iron improves menstruation
6 people found this helpful
After searching for a safe, vegetarian iron supplement, I found this one, which doesn't cause any stomach discomfort or constipation. I appreciate that I don't have to wait an hour before eating or avoid dairy or coffee. Following the recommended dosage, I feel reassured about potential poisoning. Within two weeks of starting it, my menstruation returned to normal. Knowing that Now Foods is a family-run company gives me more confidence in their products. Supplements can be beneficial or harmful, so one must choose wisely.
9
Iron raised levels
5 people found this helpful
This chelated iron works remarkably well in raising iron levels. I took two capsules daily, and while it may not suffice for a significant deficit, it helped me. I added vitamin C to my diet afterwards, and after 8 weeks, my ferritin levels rose and I felt no constipation, thanks to my high-fiber diet.
7.5
Ferritin improved dramatically
5 people found this helpful
My anaemia was never pinpointed until I realised my condition wasn't improving. A ferritin test revealed low double digits. I was taking heme iron supplements in Japan, but my levels did not rise. Since starting this Now Foods supplement, my ferritin improved for the first time. I feel much better. Initially, I took 36ml, but now that I've reached my goal, I continue with 18ml, taken only at night.
9
Iron supplementation works
6 people found this helpful
My hemoglobin was low, and as someone who doesn't enjoy eating meat, I usually struggle with iron supplements. However, this one caused no discomfort and my blood tests showed normal hemoglobin levels. I also noticed increased energy. Thank you; I'm ready to order again!
9
Easily absorbed iron
1 people found this helpful
This iron product is effective; it doesn’t cause constipation or stomach distress and is easily absorbed.
9
No constipation experienced
1 people found this helpful
Now Foods Iron does not cause constipation, setting it apart from many other iron supplements.
6
Reduced hair loss
3 people found this helpful
Although I had no subjective symptoms of anaemia, I faced significant hair loss and was feeling low. I resumed iron supplementation cautiously, alongside digestive aids, and noticed a reduction in hair shedding and improvement in mood. Women tend to lack iron, yet I must be careful due to the potential adverse effects of iron supplements on inflammation.
6
Constipation increased
1 people found this helpful
I purchased this for my iron deficiency. It certainly helps, but prolonged use can worsen constipation. I decided to supplement my iron intake through food and other health foods daily, taking it only during my menstruation.
8
We explored how iron influences food poisoning, particularly in the context of campylobacteriosis, a common foodborne illness. Our focus was on the effects of deferoxamine (DESF), an iron-chelating compound, when administered orally to mice before they were infected.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
References
- Bereswill S, Mousavi S, Weschka D, Buczkowski A, Schmidt S, et al. Iron Deprivation by Oral Deferoxamine Application Alleviates Acute Campylobacteriosis in a Clinical Murine Infection Model. Biomolecules. 2022;13. doi:10.3390/biom13010071
